比较基因组学/Comparative genomics

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This book constitutes the refereed proceedings of the 4th RECOMB Comparative Genomics Satellite Workshop, RECOMB-CG 2006, held in Montreal, Canada in September 2006.
The 17 revised full papers presented were carefully reviewed and selected from 34 initial submissions. The papers address a broad variety of aspects and components of the field of comparative genomics, ranging from new quantitative discoveries about genome structure and process to theorems on the complexity of computational problems inspired by genome comparison.

LNBI is devoted to the publication of state-of-the-art research results in bio-informatics and computational biology, at a high level and in both printed and electronic versions - making use of the well-established LNCS publication machinery. As with the LNCS mother series, refereed proceedings and post- proceedings are at the core of LNBI, however, similar to the color cover sub- lines in LNCS, tutorials and state-of-the-art surveys are also invited for LNBI. Among the topics covered are：
Genomics；Molecular sequence analysis；Recognition of genes and regulatory elements；Molecular evolution；Protein structure；Gene expression；Gene networks；Combinatorial libraries and drug design；Computational proteomics.

Reconstructing Domain Compositions of Ancestral Multi-domain Proteins
Domain Architecture in Homolog Identification
Inferring Positional Homologs with Common Intervals of Sequences
On Genome Evolution with Accumulated Change and Innovation
Paths and Cycles in Breakpoint Graphs of Random Multichromosomal Genomes
Common Intervals and Symmetric Difference in a Model-Free Phylogenomics, with an Application to Streptophyte Evolution
How Pseudo-boolean Programming Can Help Genome Rearrangement Distance Computation
Sorting by Translocations Via Reversals Theory
Inferring Gene Orders from Gene Maps Using the Breakpoint Distance
Ordering Partially Assembled Genomes Using Gene Arrangements
Evolution of Tandemly Repeated Sequences Through Duplication and Inversion
A PQ Framework for Reconstructions of Common Ancestors and Phylogeny
Intron Loss Dynamics in Mammals
Finding Maximum Likelihood Indel Scenarios
Conservation Patterns in cis-Elements Reveal Compensatory Mutations
Transcription Factor Centric Discovery of Regulatory Elements in Mammalian Genomes Using Alignment-Independent Conservation Maps
Identifiability Issues in Phylogeny-Based Detection of Horizontal Gene Transfer
Author Index