Computational Life Sciences计算生命科学/会议录
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内容提要：
This book constitutes the refereed proceedings of the First International Symposium on Computational Life Sciences, CompLife 2005, held in Konstanz, Germany in September 2005. The 21 revised full papers presented together with 3 papers of a workshop on Distributed Data Mining in the Life Sciences (LifeDDM) were carefully reviewed and selected from 49 initial submissions. The papers cover areas ranging from high-level system biology to data analysis related to mass spec traces and are organized in topical sections on systems biology, data analysis and integration, structural biology, genomics, computational proteomics, molecular informatics, molecular structure determination and simulation, and distributed data mining.
目录：
Systems Biology
Structural Protein Interactions Predict Kinase-Inhibitor Interactions in Upregulated Pancreas Tumour Genes Expression Data Biochemical Pathway Analysis via Signature Mining Recurrent Neuro-fuzzy Network Models for Reverse Engineering Gene Regulatory Interactions Data Analysis and Integration Some Applications of Dummy Point Scatterers for Phasing in Macromolecular X-Ray Crystallography BioRegistry: A Structured Metadata Repository for Bioinformatic Databases Robust Perron Cluster Analysis for Various Applications in Computational Life Science Structural Biology Multiple Alignment of Protein Structures in Three Dimensions Protein Annotation by Secondary Structure Based Alignments (PASSTA) MAPPIS: Multiple 3D Alignment of Protein-Protein Interfaces Genomics Frequent Itemsets for Genomic Profiling Gene Selection Through Sensitivity Analysis of Support Vector Machines Tile Breakpoint Graph in Ciliates Computational Proteomics ProSpect: An R Package for Analyzing SELDI Measurements Identifying Protein Biomarkers Algorithms for the Automated Absolute Quantification of Diagnostic Markers in Complex Proteomics Samples Detection of Protein Assemblies in Crystals Molecular Informatics Molecular Similarity Searching Using COSMO Screening Charges (COSMO/3PP) Increasing Diversity in In-silico Screening with Target Flexibility …… Molecular Structure Determination and Simulation Distributed Data Mining Author Index |