Stem Cells: Nuclear Reprogramming and Therapeutic Applications干细胞 256
|
读过这本书吗？
最近在读
读过
想读
还不熟悉
|
图书城书列：
加入到博客或社交网站：
|
|
我来评论这本书：
内容提要：
Understanding stem cells at the molecular level is essential to understanding their behaviour in a physiological context. This volume in our acclaimed Novartis Foundation series features animated discussion from the world’s experts in this topic on the important ethical issues that are raised by research on stem cells. They review the various regulatory regimes, which apply in different countries-a key factor in determining where future stem cell research is carried out.
Potential clinical applications covered in the book include the production of cardiomyocytes to replace damaged heart tissue, the production of insulin-producing cells for patients with diabetes, and the generation of neurons for the treatment of patients with Parkinson’s disease or spinal cord injury. Particular attention is paid to the factors that maintain stem cells in a pluripotent state or which drive them to create differentiated and lineage-committed cells in vitro and in vivo. Nuclear reprogramming, the process by which a nucleus acquires developmental potential, is covered here as well. It is relevant to stem cell research generally, and also to research on the cloning of animals by nuclear transfer. This book is an essential purchase for all those engaged in stem cell research, whether in the laboratory, the clinic or the regulatory authorities. 目录：
Symposium on Stem cells: nuclear reprogramming and therapeutic applications, held atthe Novartis Foundation, London, 2-4 March 2004.
Editors: Gregory Bock (Organizer) and Jamie goode This symposium is based onproposals made by Karin Blumerand Uwe Junker, andAdam Wilkina John Gearhart Chair's introduction Davor SoRer Whatis a stem cell? Discussion Markus Grompe Bone marrow-derived hepatocytes Discussion Irving L.Weissman Normaland neoplastic stem cells Discussion Catherine M.Verfaillie Multipotent adult progenitor cells: an update Discussion Steven A. Goldman and Fraser Sim Neural progenitor cells of the adult brain Discussion Generaldiscussion I Stem ceils in thebrain Martin Evans Embryonic stem cells: a perspective Discussion RudolfJaenisch, Konrad Hochedlinger and Kevin Eggan Nuclear cloning, epigenetic reprogramming and cellular differentiation Discussion General discussion II J. B. Gurdon, J. A. Byrne and S. Simonsson Nuclear reprogramming by Xenopus oocytes Discussion Bernardo Nadal-Ginard, Piero Anversa, Jan Kajstura and Annarosa Leri Cardiac stem cells and myocardial regeneration Discussion Bernat Soria, Enrique Roche, Juan A. Reig and Franz Martin Generation of insulin-producing cells from stem cells Discussion Anders Bjrklund Cell therapy for Parkinson's disease: problems and prospects Discussion Thomas H. Murray Ethical (and political) issues in research with human stem cells Discussion Final discussion The regulatory environment Index of contributors Subject index |